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How Zebrafish genes may save us

Évènement passé - 2020
13 mai Ouverture des portes à 19h
Evénement entre 19h30 et 22h30.
Little Temple Bar , 12 rue Princesse
75006, Paris
Next time you look down at a little fish, think twice before assuming they're inconsequential! Join us and dive into the amazing world of Zebrafish to discover how their genes aren't as different as you thought from ours, and how powerful their brain really is ;)

Fish & CRISPR: unraveling genes

Caroline Caetano Da Silva (Doctoral student, INSERM U1132)
In the past decade thousands of genes in the human body were discovered, yet scientists today struggle to understand their functions. Gene editing is a technology that enables researchers to modify genes from living organisms. In the field of genetics it happens that humans share 70% of their genes with Zebrafish. Research combining gene editing (CRISPR/Cas9) with Zebrafish became a very efficient - and affordable - method to study numerous genetic diseases. Our goal in a near future is to develop specific gene therapies for each patient.

Who are you calling "fish brain"?

Laure Mancini (Doctoral student, Université Laure Bally-Cuif, Institut Pasteur )
Despite the prejudice against their intelligence, fish do have a very complex brain with similar properties to the mammalian brain! Even better, they have an additional “superpower”: they can perfectly regenerate their brain… How is this possible? Thanks to a specialized population of cells called neural stem cells (NSCs). If you’re not yet amazed by what a fish brain can do, then come join us to find ou more about what fish neural stem cells are capable of!
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